Treatments for Skin Quality and Health

The future is self-rejuvenating

Polynucleotides don't just treat the skin, they teach it to repair itself - from within. Zero fillers, lasers, and peels. This is a regenerative medicine which gives results time & time again. Always improving, always repairing, always hydrating.

✔️ Stimulate the production of natural collagen
✔️ Improve skin texture and elasticity
✔️ Reduce fine lines and scarring
✔️ Restore youthful skin quality

This is advanced cellular regenerative technology

No need for downtime or for healing wounds

A woman receiving a polynucleotide skin treatment via syringe on her under-eye

What are Polynucleotides?

Polynucleotides are DNA fragments that are able to trigger your body's natural healing response. When injected into skin, these biocompatible molecules can activate fibroblasts — the cells responsible for producing collagen, elastin, and hyaluronic acid. It’s not a surface-level treatment, it’s cellular renovation.

The skin recognises them as healing signals, and as fibroblast activity increases, new collagen forms and the quality of tissue improves - from the inside out. Unlike many other treatments, the results don’t fade, they build gradually as they work with your biology:

Biocompatible: DNA fragments integrate naturally without foreign body reactions

Regenerative: Stimulates your own collagen rather than replacing it

Gradual: Results develop naturally over months, not days

Lasting: Effects persist as your renewed collagen continues working

Safe: Highly purified salmon-derived DNA with excellent safety profile

Studies show biological changes whereby polynucleotides increase:

  • Collagen synthesis by up to 47%

  • Skin elasticity by 23%

  • Dermal thickness by 15%

  • Patient satisfaction scores by 89%

Sources: NIH Study,

A woman receiving a cosmetic injection from Samantha in her clinic, with 'Samantha Louise' logo on the wall behind.

What They Treat

As new collagen & elastin are produced, with enhanced circulation, improvements and natural repairs seen include:

Skin Quality: Rough texture, enlarged pores & complexion improvements

Fine Lines: Dynamic & static wrinkles soften

Acne Scarring: Damaged areas are naturally filled in

Skin Laxity: Loose or crepey skin tightens, restoring firmness and snap-back

Under-Eye Rejuvenation: Dark circles improve and reduce

Neck and Décolletage: Areas often forgotten see rewed firmness, tightening, texture and tone

The Areas

Face Full-face treatment addresses overall skin quality, texture, and fine lines

Periorbital (Eye Area) Delicate under-eye skin responds particularly well to gentle regenerative treatment

Neck Horizontal necklace lines and crepey texture improve with targeted injections

Hands Age spots, thin skin, and prominent veins soften as tissue quality improves

Décolletage Sun damage and horizontal chest lines respond to polynucleotide stimulation

The Protocols

Assessment Phase We evaluate your skin quality, concerns, and healing capacity. Skin thickness, elasticity, and existing damage inform our treatment plan.

Injection Technique Ultra-fine needles deliver polynucleotides into the papillary dermis through multiple micro-injections. The process takes 30-45 minutes.

Post-Treatment Response Mild swelling and redness resolve within 24-48 hours. The real work happens beneath the surface as cellular repair begins.

Weeks 1-2: Initial healing response is activated, no visible changes yet

Weeks 4-6: First improvements in skin texture and hydration can be seen

Weeks 8-12: Collagen production peaks, fine lines will soften and pores refine

Months 3-6: Full results develop as tissue remodelling continues

Maintenance: Annual treatments maintain optimal skin quality

The Results

Booking Link Coming Soon

Safety Awareness

Polynucleotides have an excellent safety profile with minimal side effects. The treatment has been used safely in Europe for over a decade with extensive clinical data supporting its efficacy and safety.

Common responses:

  • Mild swelling at injection sites (resolves in 24-48 hours)

  • Temporary redness

  • Minor bruising

Rare complications:

  • Allergic reactions (less than 0.1% of patients)

  • Granuloma formation (extremely rare)

Suitable for if you have:

  • Early signs of aging or sun damage

  • Realistic expectations about gradual improvement

  • Commitment to the treatment series

  • Understanding that results take time

Perfect for:

  • Preventative anti-aging (late 20s onwards)

  • Skin quality concerns over specific wrinkles

  • Those wanting natural-looking improvements

  • Patients seeking collagen stimulation

This treatment is not suitable for anyone who:

  • Wants immediate dramatic changes

  • Has active skin infections or inflammation

  • Is pregnant or breastfeeding

  • Has unrealistic timeline expectations